OPTIMISATION OF DIAGNOSTICS AND DIFFERENTIAL DIAGNOSTICS DISSEMINATED PULMONARY TUBERCULOSIS

Precision medicine, technologies, and molecular diagnostics

Introduction: Genetics, cellular and molecular medicines are cutting-edge sciences and technologies that play an important role in improving human health and quality of life. In addition, medical and biological sciences have clearly shown that the onset of diseases differs from person to person due to their different genetic profiles and variations in molecular basis. Therefore, it is feasible ...

Diagnostics in pulmonary hypertension.

Pulmonary hypertension is a serious disease with a poor prognosis. Pulmonary hypertension is defined by a mean pulmonary arterial pressure over 25 mm Hg at rest or over 30 mm Hg during activity. According to the recent WHO classification from 2003 pulmonary hypertension can be categorized as pulmonary arterial hypertension, pulmonary venous hypertension, hypoxic pulmonary hypertension, chronic ...

Appropriate technology in tuberculosis diagnostics.

First, the statement that the use of the string test “will be hampered by the need for sputum induction” seems to be a misunderstanding: sputum induction added nothing to the results of the string test and was used only as a comparative test for this research. In fact, our findings clearly show that the string test alone offers better diagnostic sensitivity than sputum induction. By obviating t...

New Diagnostics for Mycobacterium tuberculosis

Which new diagnostics for tuberculosis, and when?

Recently, new diagnostic tools for tuberculosis detection and resistance testing have become available. The World Health Organization endorses new tuberculosis diagnostics by using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) process. This endorsement process takes place when limited evidence beyond test accuracy is available. There is a need to provide guidanc...